Spinach Artichoke Chicken Stuffed Pita

Featured in: One-Dish Kitchen Cooking

This Mediterranean-inspired dish combines cooked chicken breast with canned artichoke hearts, fresh spinach, and a creamy mixture of Greek yogurt and mayonnaise, bound together with mozzarella and Parmesan cheese.

Stuff the seasoned filling into pita bread pockets and bake until the cheese melts and the filling is heated through—about 15-20 minutes at 375°F.

Each serving packs 31g of protein, making it an ideal choice for those seeking substantial, flavorful meals with Mediterranean flavors.

Updated on Tue, 20 Jan 2026 10:31:00 GMT
Freshly baked spinach artichoke chicken stuffed pita pockets on a wooden board, garnished with parsley and lemon wedges. Save
Freshly baked spinach artichoke chicken stuffed pita pockets on a wooden board, garnished with parsley and lemon wedges. | spoontally.com

The first time I made these stuffed pitas, I was trying to use up leftover rotisserie chicken and a random assortment of ingredients from my fridge. My roommate walked in mid-prep, skeptically eyeing the Greek yogurt in the spinach artichoke mixture, but ended up eating two whole pitas straight from the baking sheet. Now they request them weekly.

I started bringing these to work after my microwave lunch disasters became legendary in the breakroom. Something about the pita bread protecting that cheesy, garlicky filling makes it reheat beautifully, and my coworkers actually started lingering around my desk on Tuesdays. The lemon wedges are non-negotiable now, they cut through the richness in a way I discovered completely by accident.

Ingredients

  • Chicken breast, cooked: Rotisserie chicken works beautifully here, but any leftover cooked chicken breast or thigh meat does the job
  • Artichoke hearts: Canned and drained is perfectly fine, just give them a rough chop so they distribute evenly throughout the filling
  • Fresh spinach: Frozen spinach will make the filling too watery, so stick with fresh and chop it well
  • Greek yogurt: Creates that tangy creaminess while keeping things lighter than traditional cream cheese bases
  • Light mayonnaise: Balances the yogurt and helps bind everything together without overwhelming the dish
  • Mozzarella and Parmesan: The mozzarella melts into gorgeous stretches while Parmesan brings that salty, nutty depth
  • Garlic and onion powder: This duo creates that familiar spinach artichoke flavor profile everyone recognizes
  • Dried oregano: Mediterranean herbs bridge the gap between the filling and the pita bread perfectly
  • Pita breads: Whole wheat adds nuttiness and holds up better during baking, but regular works great too

Instructions

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Preheat your oven:
Get it to 375°F and line a baking sheet with parchment paper because cheese will inevitably escape
Mix the filling:
Combine everything except the pitas in a large bowl, mixing until the chicken is evenly coated and the spinach is distributed throughout
Prep the pitas:
Carefully slice each pita in half to create pockets, being gentle not to tear through the back
Stuff generously:
Fill each pita half as full as possible without splitting the seams, using a spoon to really pack the filling in
Bake until bubbly:
Arrange on your prepared baking sheet and bake for 15-20 minutes until hot throughout and the cheese is melting
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Make fresh ice for iced coffee, cocktails, chilling ingredients, and keeping drinks cold while cooking.
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Golden-brown baked pita halves stuffed with creamy spinach artichoke chicken, served warm with melted mozzarella oozing out. Save
Golden-brown baked pita halves stuffed with creamy spinach artichoke chicken, served warm with melted mozzarella oozing out. | spoontally.com

These became my go-to after discovering my husband would actually eat spinach if it was wrapped in melted cheese and bread. Now they are in regular rotation, and I have caught him eating them cold from the fridge more than once, which I think is the ultimate compliment.

Make Ahead Magic

The filling can be mixed up to two days in advance and stored in an airtight container in the refrigerator. I actually think the flavors meld better after sitting overnight, and stuffing fresh pitas right before baking takes about five minutes.

Customization Options

Sometimes I add sun-dried tomatoes or roasted red peppers when I want to shake things up. Fresh basil or dill can replace or complement the parsley garnish depending on your mood and what is wilting in your crisper drawer.

Serving Suggestions

A crisp green salad with an acidic vinaigrette balances the richness perfectly, or serve alongside roasted vegetables for a more substantial meal. The lemon wedges are not just for show.

  • Squeeze fresh lemon over the top right before eating to brighten all the flavors
  • These reheat surprisingly well in a toaster oven if you avoid the microwave
  • Extra Parmesan sprinkled over the top during the last 2 minutes of baking creates a crispy cheese crust

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Overhead view of a Mediterranean-American spinach artichoke chicken stuffed pita on a plate, ready for a light dinner. Save
Overhead view of a Mediterranean-American spinach artichoke chicken stuffed pita on a plate, ready for a light dinner. | spoontally.com

Hope these become a regular part of your lunch rotation like they have in mine.

Recipe FAQs

Can I prepare the filling ahead of time?

Yes, you can mix the filling up to 24 hours in advance. Store it in an airtight container in the refrigerator. Stuff the pitas just before baking for best results.

What type of chicken works best?

Rotisserie chicken provides excellent flavor and saves preparation time. Alternatively, use cooked chicken breasts that you've diced or shredded. Both approaches yield tender, flavorful results.

How do I prevent the pitas from becoming too soft?

Use pitas that are slightly thicker and sturdier. Avoid over-packing the pockets and ensure your baking sheet is properly lined with parchment paper for even heat distribution.

Can I modify the filling for dietary preferences?

Absolutely. Substitute Greek yogurt with cream cheese for richness, or add sun-dried tomatoes and roasted red peppers for extra flavor. You can also adjust the cheese ratio based on preference.

What side dishes pair well with this?

A crisp green salad with lemon vinaigrette complements the filling beautifully. Roasted vegetables like zucchini or bell peppers, or a light tzatziki sauce, also work well alongside.

How should I store leftovers?

Place cooled pitas in an airtight container in the refrigerator for up to 3 days. Reheat in the oven at 350°F for 10 minutes or microwave for 1-2 minutes until warmed through.

Spinach Artichoke Chicken Stuffed Pita

Warm, fluffy pita pockets filled with creamy spinach, artichokes, and tender chicken. Perfect for a satisfying lunch or light dinner.

Prep time
20 minutes
Time to cook
20 minutes
Time required
40 minutes
Recipe by Ella Wilson


Skill level Easy

Cuisine Mediterranean-American

Makes 4 Portions

Diet preferences None specified

Needed ingredients

Chicken & Filling

01 2 cups cooked chicken breast, diced or shredded
02 1 cup canned artichoke hearts, drained and chopped
03 1 cup fresh spinach, chopped
04 1/2 cup Greek yogurt
05 1/4 cup light mayonnaise
06 1/2 cup shredded mozzarella cheese
07 1/4 cup grated Parmesan cheese
08 1 clove garlic, minced
09 1/2 teaspoon onion powder
10 1/2 teaspoon dried oregano
11 1/4 teaspoon crushed red pepper flakes, optional
12 Salt and black pepper to taste

Bread

01 4 large pita breads, whole wheat or regular

Garnish

01 2 tablespoons fresh parsley, chopped
02 2 lemons, cut into wedges

How to make it

Step 01

Preheat oven: Preheat oven to 375°F (190°C).

Step 02

Prepare filling mixture: In a large mixing bowl, combine chicken, artichoke hearts, spinach, Greek yogurt, mayonnaise, mozzarella, Parmesan, garlic, onion powder, oregano, red pepper flakes if using, salt, and black pepper. Mix until well combined.

Step 03

Cut pita breads: Slice pita breads in half to form pockets.

Step 04

Stuff pita pockets: Generously stuff each pita half with the spinach artichoke chicken mixture.

Step 05

Arrange on baking sheet: Arrange stuffed pitas on a baking sheet lined with parchment paper.

Step 06

Bake until golden: Bake for 15 to 20 minutes, or until filling is heated through and cheese is melted.

Step 07

Finish and serve: Remove from oven and garnish with chopped parsley. Serve with lemon wedges if desired.

What you need

  • Mixing bowl
  • Spoon or spatula
  • Baking sheet
  • Chef's knife
  • Parchment paper

Allergen details

Be sure to read over each ingredient for allergens. If unsure, check with your healthcare provider.
  • Contains dairy: yogurt and cheese
  • Contains eggs: mayonnaise
  • Contains gluten: pita bread
  • May contain soy: depending on mayonnaise brand

Nutrition per serving

Details here are for your information only. Don't substitute for advice from your doctor.
  • Calorie count: 385
  • Fat content: 13 grams
  • Carbohydrates: 34 grams
  • Proteins: 31 grams